Specific binding of modified ZD6474 (Vandetanib) monomer and its dimer with VEGF receptor-2

Engineering & Materials Science

• Intercellular Signaling Peptides and Proteins 79%
• Dimers 78%
• Monomers 61%
• Tumors 53%
• Dyes 35%
• Endothelial cells 30%
• Pericytes 23%
• Heterografts 19%
• Liver 12%
• Assays 12%
• Molecules 10%
• Cells 10%
• Stabilization 8%
• Imaging techniques 7%

Medicine & Life Sciences

• N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine 82%
• Vascular Endothelial Growth Factor Receptor-2 64%
• Neoplasms 16%
• Fluorescent Dyes 15%
• Endothelial Cells 11%
• In Vitro Techniques 9%
• Pericytes 9%
• matrigel 8%
• Human Umbilical Vein Endothelial Cells 7%
• Growth 7%
• Protein-Tyrosine Kinases 6%
• Heterografts 6%
• Vascular Endothelial Growth Factor A 6%
• Coloring Agents 6%
• Therapeutic Uses 6%
• Intercellular Signaling Peptides and Proteins 6%
• Spleen 5%

Chemistry

• Vandetanib 100%
• Monomer 30%
• Fluorescent Dye 27%
• Angiogenic 19%
• Tyrosine Kinase Inhibitor 18%
• Growth Factor 15%
• Antagonist 12%
• Dye 8%