Spatial distribution of elements in the brain of rats measured by synchrotron radiation X-ray fluorescence

Liu Xing Feng, Hai Qing Xiao, Xiao He, Zhi Yong Zhang, Nian Qing Liu, Yu Liang Zhao, Yu Ying Huang

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Spatial (two-dimensional) distributions of inorganic elements such as chlorine, potassium, calcium, iron, copper, and zinc in the brain slices of Wistar rats were measured by synchrotron radiation X-ray fluorescence (SRXRF) analysis. Differences in two-dimensional distribution of these elements were observed. Chlorine, calcium, and zinc were primarily concentrated in hippocampus, while the potassium concentration was relatively higher in both cerebral cortex and hippocampus. However, the distribution of copper was comparatively ruleless in the three brain regions. The cluster analysis of the elemental results shows that the spatial distribution of chlorine was correlated well with the distribution of potassium. Since SRXRF is possible to obtain a pictorial representation of the elemental concentrations in tissue sections of brain, this nuclear method may be useful to evaluate the ionic changes in injured brain tissues in relation to histological observations.

Original languageEnglish (US)
Pages (from-to)1012-1016
Number of pages5
JournalKao Neng Wu Li Yu Ho Wu Li/High Energy Physics and Nuclear Physics
Volume29
Issue number10
StatePublished - Oct 1 2005

Keywords

  • Spatial distribution
  • Synchrotron radiation X-ray fluorescence
  • Trace elements

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Nuclear and High Energy Physics

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