Small intestinal bacterial overgrowth (SIBO) was described many years ago as an important cause of maldigestion and malabsorption among individuals who had undergone upper gastrointestinal surgery or had some other major anatomical anomaly or motility disorder of the small intestine. More recently the definition of SIBO has been extended to a much larger patient population - individuals who would otherwise be classified as a functional gastrointestinal disorder but who have tested positive for SIBO, usually on the basis of a breath test. This extension of the concept of SIBO is problematic as it assumes that the available tests to diagnose SIBO are accurate, which they are not. The challenges that the diagnosis and management of this disorder pose will be explored.

Original languageEnglish (US)
Title of host publicationEssential Medical Disorders of the Stomach and Small Intestine
Subtitle of host publicationA Clinical Casebook
PublisherSpringer International Publishing
Number of pages20
ISBN (Electronic)9783030011178
ISBN (Print)9783030011161
StatePublished - Jan 1 2019


  • Breath hydrogen test
  • Irritable bowel syndrome
  • Jejunal aspiration
  • Microbiota
  • Rifaximin
  • Small intestinal bacterial overgrowth

ASJC Scopus subject areas

  • Medicine(all)


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