Small Intestinal Bacterial Overgrowth

Daniel Bushyhead, Eamonn M. Quigley

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


The term "small intestinal bacterial overgrowth" (SIBO) has been used to refer to a disorder resulting from the colonization of the small bowel by an increased number of microorganisms or by the presence of bacteria that are not usual constituents of this part of the gastrointestinal tract. Clinical presentations, often in patients with certain risk factors, can range from a full-blown malabsorption syndrome to such "functional" complaints as bloating and flatulence. SIBO is diagnosed by either culture of a small bowel aspirate or one of several breath tests. Treatment of SIBO entails risk factor modification, correction of nutritional deficiencies, and oral antibiotics.

Original languageEnglish (US)
Pages (from-to)463-474
Number of pages12
JournalGastroenterology Clinics of North America
Issue number2
StatePublished - Jun 2021


  • Antibiotics
  • Breath test
  • Malabsorption syndrome
  • Microbiome
  • Microbiota
  • Small bowel aspirate
  • Small intestinal bacterial overgrowth

ASJC Scopus subject areas

  • Gastroenterology


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