Abstract
Gastrointestinal (GI) tract small cell carcinoma (SCC) consists of a group of rare malignancies characterized by aggressive clinical history, chemotherapy-sensitivity, and very few reports of durable remission or cure. SCC has been reported in almost every organ of the GI tract. Esophagus is the most frequently reported site of GI SCC. Most of the information about treatment is derived from what we know from SCC of the lung. Treatment of extensive or advanced stage is based on platinum-containing regimens. Optimal treatment of limited-stage disease includes the use of a multimodality approach combining chemotherapy, radiation, and possibly surgery.
Original language | English (US) |
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Title of host publication | Textbook of Uncommon Cancer, Third Edition |
Publisher | Wiley |
Pages | 430-435 |
Number of pages | 6 |
ISBN (Print) | 0470012021, 9780470012024 |
DOIs | |
State | Published - Jul 11 2006 |
Keywords
- Extensive stage
- Extrapulmonary
- Gastrointestinal tract
- Limited stage
- Platinum chemotherapy
- Poorly-differentiated carcinoma
- Review
- Small cell carcinoma
ASJC Scopus subject areas
- General Medicine