TY - JOUR
T1 - Small cell carcinoma of the ovary with hypercalcemia and ectopic parathyroid hormone production
AU - Chen, Lei
AU - Dinh, Tri A.
AU - Haque, Abida
PY - 2005/4
Y1 - 2005/4
N2 - Small cell carcinoma of the ovary is a rare malignant tumor of the ovary. It is the most common undifferentiated ovarian carcinoma in young women. Approximately two thirds of patients with ovarian small cell carcinoma have hypercalcemia. The mechanism of development of hypercalcemia is unclear, although parathyroid hormone-related protein has been found in some of the cases. Parathormone expression in tumor cells, rarely reported, was seen in this case, suggesting that ectopic parathyroid hormone production by the tumor cells may be the cause of hypercalcemia.
AB - Small cell carcinoma of the ovary is a rare malignant tumor of the ovary. It is the most common undifferentiated ovarian carcinoma in young women. Approximately two thirds of patients with ovarian small cell carcinoma have hypercalcemia. The mechanism of development of hypercalcemia is unclear, although parathyroid hormone-related protein has been found in some of the cases. Parathormone expression in tumor cells, rarely reported, was seen in this case, suggesting that ectopic parathyroid hormone production by the tumor cells may be the cause of hypercalcemia.
UR - http://www.scopus.com/inward/record.url?scp=16344377079&partnerID=8YFLogxK
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U2 - 10.5858/2005-129-531-sccoto
DO - 10.5858/2005-129-531-sccoto
M3 - Article
C2 - 15794681
AN - SCOPUS:16344377079
SN - 0003-9985
VL - 129
SP - 531
EP - 533
JO - Archives of Pathology and Laboratory Medicine
JF - Archives of Pathology and Laboratory Medicine
IS - 4
ER -