Sleep disorders in spinal cord injury

Richard J. Castriotta, Mark C. Wilde, Sandeep Sahay

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Pathophysiological changes resulting from spinal cord injury (SCI) result in four groups of sleep-related problems: (1) sleep-disordered breathing with hypoventilation and obstructive sleep apnea; (2) circadian rhythm disorders with disruption of melatonin and body temperature rhythms; (3) sensorimotor problems with restless legs and periodic limb movements; and (4) insomnia with multifactorial causes, including pain, paresthesias, mood and anxiety disorders and voiding problems in addition to the above. Sleep disorders are under-recognized in patients with SCI because sleep-related respiratory problems may be asymptomatic, and thus are not investigated. In patients with SCI, sleep-disordered breathing leads to neurocognitive impairment adversely affecting neurorehabilitation.

Original languageEnglish (US)
Pages (from-to)643-653
Number of pages11
JournalSleep Medicine Clinics
Issue number4
StatePublished - Jan 1 2012


  • Circadian rhythm disorder
  • Hypoventilation
  • Insomnia
  • Melatonin
  • Restless legs
  • Sleep apnea
  • Sleep-disordered breathing
  • Spinal cord injury

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health


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