In this patient with a renal allograft, conversion from tacrolimus to sirolimus was associated with the appearance of severe thrombotic microangiopathy. Sirolimus discontinuation resulted was followed by full recovery, suggesting that the sirolimus played a role in the thrombotic microangiopathy.

Original languageEnglish (US)
Pages (from-to)229-230
Number of pages2
JournalAmerican Journal of Transplantation
Issue number2
StatePublished - Feb 2003


  • Hemolytic uremic syndrome
  • Thrombotic microangiopathy

ASJC Scopus subject areas

  • Immunology

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