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Single shot line-field optical coherence elastography

Chih Hao Liu, Alexander Schill, Manmohan Singh, Chen Wu, Jiasong Li, Zhaolong Han, Raksha Raghunathan, Tina Kazemi, Achuth Nair, Thomas Hsu, Kirill V. Larin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Elastic wave imaging optical coherence elastography (EWI-OCE) is an emerging technique that can quantify local biomechanical properties of tissues. However, long acquisition times make this technique unfeasible for clinical use. Here, we demonstrate a noncontact single shot line-field OCE technique using a line-field interferometer and an air-pulse delivery system. The spatial-temporal elastic wave propagation profile was acquired in a single shot and used to quantify the elastic wave group velocity in tissue. Results on tissue-mimicking phantoms and chicken breast muscle agreed well with mechanical compression testing, demonstrating that the presented method can effectively reduce the OCE acquisition time to a few milliseconds in biological application.

Original languageEnglish (US)
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX
EditorsValery V. Tuchin, Joseph A. Izatt, James G. Fujimoto
PublisherSPIE
ISBN (Electronic)9781628419313
DOIs
StatePublished - 2016
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX - San Francisco, United States
Duration: Feb 15 2016Feb 17 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9697
ISSN (Print)1605-7422

Conference

ConferenceOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX
Country/TerritoryUnited States
CitySan Francisco
Period2/15/162/17/16

Keywords

  • Carré phase shift
  • crosscorrelation
  • Line-field optical coherence tomography
  • optical coherence elastography
  • surface wave

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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