Simultaneous Scalp, Skull, Kidney, and Pancreas Transplant from a Single Donor: Insights from a 5-Year Follow-Up

Yelda Jozaghi, Edward I. Chang, Mark W. Clemens, Matthew M. Hanasono, Michael Klebuc, Peirong Yu, A. Osama Gaber, Jesse C. Selber

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Summary: This report provides a 5-year follow-up on the first reported simultaneous scalp, calvarium, kidney, and pancreas transplant. The previously published case report represented both the first composite calvarial-scalp transplant and combination of a vascularized composite allotransplantation with double organ transplantation. Over the ensuing 5 years, the patient underwent a single episode of acute scalp rejection successfully managed with intravenous Solu-Medrol, one resection of a basal cell carcinoma on the native scalp, hardware removal, and bony contouring. In addition, the patient developed seizures secondary to delayed, postirradiation cerebral necrosis requiring craniotomy and resection. His seizures were ultimately controlled. Currently, more than 5 years after his multiorgan transplant, the patient continues to have excellent allograft function and a very satisfactory aesthetic outcome, demonstrating that in certain cases, combined vascularized composite allotransplantation with solid organ transplantation can be performed safely without compromising the solid organ transplantation.

Original languageEnglish (US)
Pages (from-to)1318-1321
Number of pages4
JournalPlastic and Reconstructive Surgery
Volume151
Issue number6
DOIs
StatePublished - Jun 1 2023

Keywords

  • Humans
  • Scalp/surgery
  • Pancreas Transplantation
  • Follow-Up Studies
  • Skull
  • Kidney
  • Graft Rejection/pathology

ASJC Scopus subject areas

  • Surgery

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