Simultaneous measurement of cortical potassium, calcium, and magnesium levels measured in head injured patients using microdialysis with ion chromatography

J. Clay Goodman, A. B. Valadka, S. P. Gopinath, M. Uzura, Robert G. Grossman, C. S. Robertson

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Potassium, calcium and magnesium were measured in 3717 microdialysate samples in 43 patients with head injury experiencing refractory increased ICP, episodes of jugular venous oxygen desaturation and brain death. Cation analysis was performed with 'ion chromatography'. Potassium levels remained stable until severe physiological deterioration occurred, whereupon they increased 100 400%, usually associated with release of amino-acids including glutamate, aspartate, and taurine into the extracellular space. The magnesium and calcium levels remained unchanged, regardless of the severity of physiological deterioration.

Original languageEnglish (US)
Pages (from-to)35-37
Number of pages3
JournalActa Neurochirurgica, Supplement
Volume1999
Issue numberSUPPL. 75
DOIs
StatePublished - 1999

Keywords

  • Cortical potassium and calciumlevels
  • Head injury
  • Ion chromatography
  • Microdialysis

ASJC Scopus subject areas

  • Medicine(all)
  • Clinical Neurology

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