@article{b5245bdf25b2456ba4e3c24effe60ed5,
title = "Simultaneous infection with enterobacteriaceae and pseudomonas aeruginosa harboring multiple carbapenemases in a returning traveler colonized with candida auris",
abstract = "We report our clinical experience treating a critically ill patient with polymicrobial infections due to multidrug-resistant Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa in a 56-year-old woman who received health care in India and was also colonized by Candida auris. A precision medicine approach using whole-genome sequencing revealed a multiplicity of mobile elements associated with NDM-1, NDM-5, and OXA-181 and, supplemented with susceptibility testing, guided the selection of rational antimicrobial therapy.",
keywords = "Candida auris, Carbapenemase, Enterobacteriaceae, NDM, Polymicrobial infection, Pseudomonas aeruginosa",
author = "Ayesha Khan and Shropshire, {William C.} and Blake Hanson and Dinh, {An Q.} and Audrey Wanger and Luis Ostrosky-Zeichner and Arias, {Cesar A.} and Miller, {William R.}",
note = "Funding Information: This work was supported by the National Institutes of Health grants R01 AI134637, R21 AI143229, and K24 AI121296, a UTHealth presidential award, a University of Texas System STARS award, and the Texas Medical Center Health Policy Institute Funding Program to C.A.A. W.R.M was supported by NIH/NIAID grant K08 AI135093. The funding agency had no role in experimental design, data collection, or interpretation of this work. Funding Information: L.O.-Z. has received grants and/or speaking and consulting honoraria from Merck, Astellas, Pfizer, Gilead, Cidara, Scynexis, Achaogen, Insmed, Paratek, GSK, Nabriva, Shionogi, F2G, Mayne, and Viracor. C.A.A. has received grants from Merck, MeMed Diagnostics, and Entasis Pharmaceuticals. W.R.M. has received grants and/or honoraria from Merck, Entasis, Achaogen, and Shionogi. A.K., W.C.S., B.H., A.Q.D., and A.W. report no conflicts of interest. Publisher Copyright: {\textcopyright} 2020 American Society for Microbiology. All rights reserved.",
year = "2020",
month = jan,
day = "27",
doi = "10.1128/AAC.01466-19",
language = "English (US)",
volume = "64",
journal = "Antimicrobial Agents and Chemotherapy",
issn = "0066-4804",
publisher = "American Society for Microbiology",
number = "2",
}