Sex differences in the hepatic in vitro metabolism of 4-androstene-3, 17-dione in rainbow trout, Salmo gairdnerii

Thu Hansson, Jan Åke Gustafsson

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

The metabolism of androstenedione by liver microsomes from rainbow trout, Salmo gairdnerii, at different stages of sexual development was studied, 17-Hydroxysteroid oxidoreductase activity in male trout increased significantly during the spawning period, while no such increase was seen in female trout. On the other hand, 6β-hydroxylase activity was significantly lower in maturing female trout when compared to juvenile and mature trout of both sexes. 5α-Reductase and 16-hydroxylase activities exhibited no sex-dependent variations during the period of sexual development in trout. A possible role for the liver in regulation of steroid biosynthesis in fish is discussed.

Original languageEnglish (US)
Pages (from-to)181-188
Number of pages8
JournalGeneral and Comparative Endocrinology
Volume44
Issue number2
DOIs
StatePublished - Jun 1981

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Endocrinology

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