Severe nonendemic pemphigus foliaceus presenting in the postpartum period

Hossein C. Nousari, Arash Kimyai-Asadi, Nooshin Ketabchi, Luis A. Diaz, Grant J. Anhalt

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The new onset of pemphigus in the postpartum period is exceedingly rare with only 1 case previously reported in the literature. We describe a 31- year-old woman who developed extensive denudation of her skin shortly after delivering her second child. Histologic examination, immunofluorescence testing, and immunoprecipitation with desmoglein 1 confirmed the diagnosis of pemphigus foliaceus. The patient responded to treatment with prednisone, cyclophosphamide, and plasmapheresis. The effect of the postpartum period on the onset and exacerbation of immune-mediated bullous diseases is discussed.

Original languageEnglish (US)
Pages (from-to)845-846
Number of pages2
JournalJournal of the American Academy of Dermatology
Issue number5 SUPPL. 1
StatePublished - 1999

ASJC Scopus subject areas

  • Dermatology


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