Severe ischemic injury to the proximal airway following lung transplantation: Immediate and long-term effects on bronchial cartilage

A. E. Frost, C. A. Keller, P. T. Cagle, G. Noon, D. Short, J. Young, J. R. Viets

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Ischemia due to interruption of the bronchial circulation has been recognized as a cause of immediate postoperative anastomotic dehiscence in lung and heart-lung transplant recipients. Since patients do not ordinarily survive such major ischemic insults, the long-term effects of airway ischemia and the differentiation of these effects from those of transplant rejection and infection have not been clearly defined. We describe a patient who suffered extensive airway ischemia, necrosis, and subsequent diffuse airway stenosis. Loss of the bronchial circulation with variable ischemia may be a major cause of late airway abnormality responsible for significant morbidity and mortality in transplant recipients.

Original languageEnglish (US)
Pages (from-to)1899-1901
Number of pages3
JournalCHEST
Volume103
Issue number6
DOIs
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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