Sequential postoperative assessment of left ventricular performance with gated cardiac blood pool imaging following aortocoronary bypass surgery

Lawrence A. Reduto, Gerald M. Lawrie, John Warren Reid, Hartwell H. Whissenand, George P. Noon, Donna Kanon, B. Math, Michael E. DeBakey, Richard R. Miller

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

The comparative effects of normothermic intermittent ischemic arrest (IIA) and cardioplegia (C) on left ventricular (LV) performance were assessed by gated cardiac blood pool imaging in 57 patients undergoing aortocoronary bypass surgery. In 34 patients, IIA was employed; 23 patients received C. Patients were studied preoperatively, sequentially in the immediate postoperative period at 30-minute intervals, and at 1 week after the operation. C and IIA groups did not differ in mean (± SEM) age, anginal class, number of diseased vessels, previous myocardial infarction, or preoperative ejection fraction (EF) (50 ± 3% vs 50 ± 2% [p = ns]). Aortic cross clamp time was greater with C than IIA (50 ± 5 minutes vs 28 ± 3 minutes [p = 0.001]). During the six sequential postoperative studies, transient LV dysfunction (≥ 7% decrease in absolute EF) was observed in 10 patients receiving C and in 16 patients receiving IIA. By time of discharge, 24 of 26 patients had returned to preoperative EF. Mean EF at discharge in the cardioplegia group did not differ compared to preoperative EF; in the IIA group, EF increased compared to preoperative EF (50 ± 2% vs 55 ± 2% [p < 0.01]). These data suggest that in patients with normal preoperative LV performance both C and IIA afford satisfactory myocardial preservation during aortocoronary bypass surgery.

Original languageEnglish (US)
Pages (from-to)59-66
Number of pages8
JournalAmerican Heart Journal
Volume101
Issue number1
DOIs
StatePublished - Jan 1981

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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