@inproceedings{4b9e39aaff1249f2844f4a88df1be791,
title = "Semiconductor light-emitting devices with in-built bioreaction chambers",
abstract = "We demonstrate complete integration of a fluorescence-based assay in that the analyte well is also an optical emitter. Laser machining is used to create 'active micro-wells' within semiconductor light emitting diode and laser structures. These are then used to optically excite fluorescently-labelled beads in solution within the well. The results show efficient illumination on a par with traditional lamp-based excitation. This technology therefore provides active micro-well plates with completely localized excitation, confined to the analysis well, that can be engineered via the micro-well geometry. The micro-wells have also been machined within the cavity of lasing semiconductor structures and coherent emission maintained. Thus lasing multi-well plates are also realizable.",
keywords = "Fluorescence, Optoelectronics, Semiconductor lasers",
author = "Summers, {H. D.} and Matthews, {D. R.} and Errington, {R. J.} and Njoh, {K. L.} and Smith, {P. J.} and Goater, {A. D.} and Burt, {J. P H} and Rizvi, {N. H.} and A. Menachery and Morris, {D. J.}",
note = "Copyright: Copyright 2008 Elsevier B.V., All rights reserved.; Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V ; Conference date: 22-01-2007 Through 24-01-2007",
year = "2007",
doi = "10.1117/12.700411",
language = "English (US)",
isbn = "0819465542",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V",
}