Abstract
We report herein on a self-powered, self-contained microfluidic-based chip designed to separate plasma from whole blood, and then execute an assay of a multiplexed panel of plasma biomarker proteins. The power source is based upon a chemical reaction that is catalytically triggered by the push of a button on the chip. We demonstrate assays of a dozen blood-based protein biomarkers using this automated, self-contained device. This platform can potentially permit high throughput, accurate, multiplexed blood diagnostic measurements in remote locations and by minimally trained individuals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2016-2020 |
| Number of pages | 5 |
| Journal | Lab on a Chip |
| Volume | 9 |
| Issue number | 14 |
| DOIs | |
| State | Published - Jan 1 2009 |
ASJC Scopus subject areas
- Bioengineering
- Biochemistry
- General Chemistry
- Biomedical Engineering
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