Sclerosing extramedullary hematopoietic tumor involving lesser omentum and ligamentum teres in liver explant

Youngmee Kwon, Eunsil Yu, Jooryung Huh, Seung Kyu Lee, Jae Y. Ro

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

A 47-year-old patient who presented with a 2-year history of hepatitis B virus-associated liver cirrhosis underwent a liver transplantation. The explanted liver was grossly enlarged and diffusely cirrhotic. The lesser omentum and ligamentum teres revealed a 4 cm ill-defined mass that, on sectioning, showed a gray-white appearance. Extramedullary hematopoiesis on a fibrosclerotic background constituted this mass, but there was also extramedullary hematopoiesis within the liver cords and possibly within the omentum. A bone marrow study also showed chronic idiopathic myelofibrosis. Acute rejection ensued despite immunosuppression and the patient continued to deteriorate and expired. Sclerotic extramedullary hematopoietic tumor is rare, has an unfavorable prognosis, and may mark the end stage of chronic myeloproliferative disorder.

Original languageEnglish (US)
Pages (from-to)227-232
Number of pages6
JournalAnnals of Diagnostic Pathology
Volume8
Issue number4
DOIs
StatePublished - Aug 2004

Keywords

  • chronic idiopathic myelofibrosis
  • liver explant
  • Sclerosing extramedullary hematopoietic tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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