Safety, perioperative, and early functional outcomes of vapor incision technique using the GreenLight XPS 180 W system: Direct comparison with photoselective vaporization of the prostate

Mounsif Azizi, Côme Tholomier, Malek Meskawi, Pierre Alain Hueber, Roger F. Valdivieso, Abdullah M. Alenizi, Emad Rajih, Marc Zanaty, Mahmood A. Hai, Ricardo R. Gonzalez, Gregg R. Eure, Lewis S. Kriteman, Vincent Misrai, Kevin C. Zorn

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Objectives: To compare perioperative parameters, safety, and short-term functional outcomes between GreenLight 180 W-XPS photoselective vaporization of the prostate (PVP) and vapor incision technique (VIT). Materials and Methods: A total of 956 men were treated at five high-volume centers in Canada and the United States between 2000 and 2014 for benign prostatic hyperplasia. Perioperative parameters, complications, and early functional outcomes were retrospectively compared. One-to-one propensity score matching was performed to adjust for baseline differences between treatment groups. Subgroup stratified comparative analysis was performed according to preoperative prostate volume 80 cc or less vs greater than 80 cc on transrectal ultrasound (259 and 185 patients, respectively). Results: VIT allowed greater energy delivery and energy density, but operative time and laser time were longer with greater use of MoXy fibers when compared with PVP (all p < 0.05). Improvements in outcomes at 6 months, including International Prostate Symptom Score, quality of life score, and uroflowmetry parameters, were significantly greater after VIT when compared with baseline. VIT was associated with significantly greater 6-month prostate-specific antigen (PSA) reduction (63% vs 50%, p = 0.01). No differences in intraoperative complications were observed between treatment groups. Conclusion: VIT is safe and efficacious, providing greater improvements in functional outcomes and PSA reduction at 6 months in comparison with PVP. These results reflect the larger amount of adenoma removed. Yet, it is associated with longer operative time and greater use of MoXy fibers. Long-term follow-up is needed to accurately assess functional outcomes and retreatment rates.

Original languageEnglish (US)
Pages (from-to)43-49
Number of pages7
JournalJournal of Endourology
Volume31
Issue number1
DOIs
StatePublished - 2017

Keywords

  • benign prostatic hyperplasia
  • laser
  • prostate

ASJC Scopus subject areas

  • Urology

Fingerprint

Dive into the research topics of 'Safety, perioperative, and early functional outcomes of vapor incision technique using the GreenLight XPS 180 W system: Direct comparison with photoselective vaporization of the prostate'. Together they form a unique fingerprint.

Cite this