Safety of same-day thyroidectomy: Meta-analysis and systematic review

Helmi Khadra, Salah Mohamed, Adam Hauch, John Carter, Tian Hu, Emad Kandil

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Background: Performance of thyroid surgery as a same day surgery procedure has been a controversial topic. This study aimed to compare the safety and efficacy of outpatient thyroid surgery with inpatient thyroid surgery by meta-analysis of current literature. Methods: Articles were identified from the following keyword searches: outpatient thyroidectomy/thyroid surgery, same day thyroidectomy/thyroid surgery. Outcomes included perioperative complications including recurrent laryngeal nerve (RLN) injury, hypocalcemia, and readmissions. Data were extracted following review of appropriate studies by authors and random effects models were used. Results: 34 potentially relevant publications were identified and 14 studies fulfilled the predetermined inclusion criteria, totaling 10,478 patients, 4,565 of whom were discharged the same day following thyroid surgery. There was no difference in malignancy rate between the two groups (95% CI, 0.84-2.31; P=0.196). Inpatient group were 2.23 times (95% CI, 1.36-3.36; P=0.001) more likely to develop transient RLN injury and 2.32 times (95% CI, 1.06-5.06; P=0.034) more likely to have documented transient hypocalcemia compared to outpatients. Inpatient groups were 2.10 times (95% CI, 1.33-3.33; P=0.002) more likely to have documented other complications. The two groups also had similar readmission rates (95% CI, 0.71-1.41; P=1.000). Conclusions: Our meta-analysis suggests that discharging selective patients the same day after a thyroid surgery is as safe, feasible, and efficacious as admitting them for observation. Admitting patients after thyroid surgery is associated with higher reported risk of complications.

Original languageEnglish (US)
Pages (from-to)292-301
Number of pages10
JournalGland Surgery
Issue number4
StatePublished - Aug 1 2017


  • Outpatient thyroid surgery
  • Outpatient thyroidectomy
  • Same day thyroid surgery
  • Same day thyroidectomy

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Safety of same-day thyroidectomy: Meta-analysis and systematic review'. Together they form a unique fingerprint.

Cite this