Role of Rapid Diagnostics in Diagnosis and Management of Patients With Sepsis

Taryn A. Eubank, S. W. Long, Katherine K. Perez

Research output: Contribution to journalArticle

Abstract

Delayed administration of active anti-infective therapy is associated with increased rates of adverse events, mortality, and costs among sepsis patients. Inherent limitations of conventional culture identification methods and the lengthy turnaround time of antimicrobial susceptibility testing are significant barriers to the timely delivery of life-saving therapy, particularly among antibiotic-resistant infections. Culture-independent diagnostic techniques that detect pathogens and antimicrobial resistance genes within clinical samples present a tremendous benefit to timely diagnosis and management of patients. Improved outcomes for rapid intervention with rapid diagnostics have been documented and include decreased mortality rates, decreased health care delivery costs, and faster delivery of appropriate therapeutics.

Original languageEnglish (US)
Pages (from-to)S103-S109
JournalThe Journal of infectious diseases
Volume222
Issue numberSupplement_2
DOIs
StatePublished - Jul 21 2020

Keywords

  • antimicrobial stewardship
  • rapid diagnostic testing
  • sepsis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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