TY - JOUR
T1 - Role of rapid diagnostics in diagnosis and management of patients with sepsis
AU - Eubank, Taryn A.
AU - Long, S. W.
AU - Perez, Katherine K.
N1 - © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: [email protected].
PY - 2021
Y1 - 2021
N2 - Delayed administration of active anti-infective therapy is associated with increased rates of adverse events, mortality, and costs among sepsis patients. Inherent limitations of conventional culture identification methods and the lengthy turnaround time of antimicrobial susceptibility testing are significant barriers to the timely delivery of life-saving therapy, particularly among antibioticresistant infections. Culture-independent diagnostic techniques that detect pathogens and antimicrobial resistance genes within clinical samples present a tremendous benefit to timely diagnosis and management of patients. Improved outcomes for rapid intervention with rapid diagnostics have been documented and include decreased mortality rates, decreased health care delivery costs, and faster delivery of appropriate therapeutics.
AB - Delayed administration of active anti-infective therapy is associated with increased rates of adverse events, mortality, and costs among sepsis patients. Inherent limitations of conventional culture identification methods and the lengthy turnaround time of antimicrobial susceptibility testing are significant barriers to the timely delivery of life-saving therapy, particularly among antibioticresistant infections. Culture-independent diagnostic techniques that detect pathogens and antimicrobial resistance genes within clinical samples present a tremendous benefit to timely diagnosis and management of patients. Improved outcomes for rapid intervention with rapid diagnostics have been documented and include decreased mortality rates, decreased health care delivery costs, and faster delivery of appropriate therapeutics.
KW - Antimicrobial stewardship
KW - Rapid diagnostic testing
KW - Sepsis
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U2 - 10.1093/INFDIS/JIAA263
DO - 10.1093/INFDIS/JIAA263
M3 - Article
C2 - 32691836
AN - SCOPUS:85088419771
SN - 0022-1899
VL - 222
SP - S103-S109
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - Supplement_2
ER -