Role of Oxidative Stress in Disease Progression in Stage B, a Pre-cursor of Heart Failure

Arvind Bhimaraj, W. H.Wilson Tang

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations

Abstract

Oxidative stress represents a persistent imbalance between the production and the compensation of reactive oxygen species. Though predominantly found in advanced heart failure, the most frequent " at-risk" condition has been associated with underlying oxidative stress. It is therefore conceivable that timely detection and early intervention to reduce oxidative stress processes provide an opportunity to prevent disease progression to overt heart failure. This article reviews the current understanding of the current evidence of oxidative stress involvement in the pathophysiology of human heart failure and its potential therapeutic interventions in patients with Stage A and B heart failure.

Original languageEnglish (US)
Pages (from-to)101-111
Number of pages11
JournalHeart Failure Clinics
Volume8
Issue number1
DOIs
StatePublished - Jan 2012

Keywords

  • Oxidative stress
  • Progression of heart failure
  • Stage B heart failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Role of Oxidative Stress in Disease Progression in Stage B, a Pre-cursor of Heart Failure'. Together they form a unique fingerprint.

Cite this