Role of intestinal flora in metabolism of agrochemicals conjugated with glutathione

J. E. Bakke; Jan-Ake Gustafsson

doi:10.3109/00498258609038982

Role of intestinal flora in metabolism of agrochemicals conjugated with glutathione

J. E. Bakke, Jan-Ake Gustafsson

Houston Methodist

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

1. Intestinal processes which mediate the metabolic fate of glutathione conjugates of xenobiotics are reviewed. 2. The role of the intestinal microflora in the metabolism of premercapturic acid pathway metabolites is discussed. 3. The possible significance of mercapturic acid pathway metabolite catabolism in the bioaccumulation of methylthio-containing residues in the environment is presented.

Original language	English (US)
Pages (from-to)	1047-1056
Number of pages	10
Journal	Xenobiotica
Volume	16
Issue number	10-11
DOIs	https://doi.org/10.3109/00498258609038982
State	Published - Jan 1 1986

ASJC Scopus subject areas

Biochemistry
Toxicology
Pharmacology
Health, Toxicology and Mutagenesis

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10.3109/00498258609038982

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title = "Role of intestinal flora in metabolism of agrochemicals conjugated with glutathione",

abstract = "1. Intestinal processes which mediate the metabolic fate of glutathione conjugates of xenobiotics are reviewed. 2. The role of the intestinal microflora in the metabolism of premercapturic acid pathway metabolites is discussed. 3. The possible significance of mercapturic acid pathway metabolite catabolism in the bioaccumulation of methylthio-containing residues in the environment is presented.",

author = "Bakke, {J. E.} and Jan-Ake Gustafsson",

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N2 - 1. Intestinal processes which mediate the metabolic fate of glutathione conjugates of xenobiotics are reviewed. 2. The role of the intestinal microflora in the metabolism of premercapturic acid pathway metabolites is discussed. 3. The possible significance of mercapturic acid pathway metabolite catabolism in the bioaccumulation of methylthio-containing residues in the environment is presented.

AB - 1. Intestinal processes which mediate the metabolic fate of glutathione conjugates of xenobiotics are reviewed. 2. The role of the intestinal microflora in the metabolism of premercapturic acid pathway metabolites is discussed. 3. The possible significance of mercapturic acid pathway metabolite catabolism in the bioaccumulation of methylthio-containing residues in the environment is presented.

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ER -

Role of intestinal flora in metabolism of agrochemicals conjugated with glutathione

Abstract

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