Robotic implantation of biodegradable regenerative urinary conduit: Experimental study

Andre Luis De Castro Abreu, Raed A. Azhar, Andre K. Berger, Sameer Chopra, Arnaud Marien, Michael Santomauro, Raj Satkunasivam, Yi Sun, Monish Aron, Osamu Ukimura, Mihir M. Desai, Inderbir S. Gill

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Purpose: To determine the feasibility and develop a robotic technique for intracorporeal implantation of a biodegradable tubular scaffold seeded with adipose-sourced smooth muscle cells (Neo-Urinary-Conduit) that, when implanted as a conduit for urinary diversion, facilitates regeneration of native-like neourinary tissue. Materials and Methods: Robotic NUC implantation was performed in two fresh male cadavers. The greater omentum was widely detached from the greater curvature of the stomach, in preparation for final wrapping of the conduit. Bilateral ureters were mobilized for implantation. The NUC, with two precreated ureteral openings, was inserted into the abdomen. Bilateral, stented uretero-NUC anastomoses were created. The NUC was circumferentially wrapped with the predissected omentum, exteriorized through the abdominal wall, and maturated. Results: Both procedures were successfully completed intracorporeally. Operative time for NUC implantation was 90 and 100 minutes, respectively. Examination of gross anatomy showed no injury to other organs. There was no omental kinking, rotation, eversion, or stripping from the NUC. Bilateral stents were confirmed to be in situ with the proximal coil in the kidney. Uretero-NUC anastomoses and omentum were tension free. The entire NUC, including its distal edge and posterior aspect, was circumferentially wrapped 360 degrees. Conclusion: We demonstrated the feasibility and developed a robotic technique for intracorporeal implantation of a biodegradable regenerative urinary conduit. This study serves as the foundation for the robotic surgical technique before the clinical application.

Original languageEnglish (US)
Pages (from-to)52-57
Number of pages6
JournalJournal of Endourology
Issue number1
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Urology
  • Medicine(all)


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