TY - JOUR
T1 - Rhabdomyosarcoma of the Temporal Bone
T2 - Is Surgical Resection Necessary?
AU - Goepfert, Helmuth
AU - Cangir, Ayten
AU - Lindberg, Robert
AU - Ayala, Alberto
PY - 1979/6
Y1 - 1979/6
N2 - Three patients had embryonal rhabdomyosarcoma of the temporal bone. Their clinical appearances demonstrated the following characteristics: symptoms of an acute process in the middle ear cleft and mastoid, a rapidly growing polypoid mass that was visible in the middle ear and external auditory canal, and seventh nerve involvement and destruction of bone. Definitive treatment with the use of systemic chemotherapy and radiation therapy to the invaded structures was followed by maintenance chemotherapy for up to 24 months. Surgical treatment was sufficient to obtain adequate biopsy material. All patients recovered variable degrees of motor nerve functions. One patient experienced a meningococcal meningitis years after treatment; this condition resulted in total deafness. The results suggest that multiple-drug chemotherapy and radiation therapy for all involved areas are the mainstay of treatment for this disease entity.
AB - Three patients had embryonal rhabdomyosarcoma of the temporal bone. Their clinical appearances demonstrated the following characteristics: symptoms of an acute process in the middle ear cleft and mastoid, a rapidly growing polypoid mass that was visible in the middle ear and external auditory canal, and seventh nerve involvement and destruction of bone. Definitive treatment with the use of systemic chemotherapy and radiation therapy to the invaded structures was followed by maintenance chemotherapy for up to 24 months. Surgical treatment was sufficient to obtain adequate biopsy material. All patients recovered variable degrees of motor nerve functions. One patient experienced a meningococcal meningitis years after treatment; this condition resulted in total deafness. The results suggest that multiple-drug chemotherapy and radiation therapy for all involved areas are the mainstay of treatment for this disease entity.
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U2 - 10.1001/archotol.1979.00790180008002
DO - 10.1001/archotol.1979.00790180008002
M3 - Article
C2 - 454281
AN - SCOPUS:0018746566
VL - 105
SP - 310
EP - 313
JO - Archives of Otolaryngology
JF - Archives of Otolaryngology
SN - 0003-9977
IS - 6
ER -