RFID tag helix antenna sensors for wireless drug dosage monitoring

Haiyu Huang, Peisen Zhao, Pai Yen Chen, Yong Ren, Xuewu Liu, Mauro Ferrari, Ye Hu, Deji Akinwande

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Miniaturized helix antennas are integrated with drug reservoirs to function as RFID wireless tag sensors for real-time drug dosage monitoring. The general design procedure of this type of biomedical antenna sensors is proposed based on electromagnetic theory and finite element simulation. A cost effective fabrication process is utilized to encapsulate the antenna sensor within a biocompatible package layer using PDMS material, and at the same time form a drug storage or drug delivery unit inside the sensor. The in vitro experiment on two prototypes of antenna sensor-drug reservoir assembly have shown the ability to monitor the drug dosage by tracking antenna resonant frequency shift from 2.4-2.5-GHz ISM band with realized sensitivity of 1.27 μl/MHz for transdermal drug delivery monitoring and 2.76-μl/MHz sensitivity for implanted drug delivery monitoring.

Original languageEnglish (US)
Article number1700108
JournalIEEE Journal of Translational Engineering in Health and Medicine
Issue number1
StatePublished - 2014


  • Drug delivery system
  • RFID
  • electrically small antenna
  • helix antenna
  • medical implants
  • wireless sensor

ASJC Scopus subject areas

  • Biomedical Engineering


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