Abstract
Miniaturized helix antennas are integrated with drug reservoirs to function as RFID wireless tag sensors for real-time drug dosage monitoring. The general design procedure of this type of biomedical antenna sensors is proposed based on electromagnetic theory and finite element simulation. A cost effective fabrication process is utilized to encapsulate the antenna sensor within a biocompatible package layer using PDMS material, and at the same time form a drug storage or drug delivery unit inside the sensor. The in vitro experiment on two prototypes of antenna sensor-drug reservoir assembly have shown the ability to monitor the drug dosage by tracking antenna resonant frequency shift from 2.4-2.5-GHz ISM band with realized sensitivity of 1.27 μl/MHz for transdermal drug delivery monitoring and 2.76-μl/MHz sensitivity for implanted drug delivery monitoring.
Original language | English (US) |
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Article number | 1700108 |
Journal | IEEE Journal of Translational Engineering in Health and Medicine |
Volume | 2 |
Issue number | 1 |
DOIs | |
State | Published - 2014 |
Keywords
- Drug delivery system
- RFID
- electrically small antenna
- helix antenna
- medical implants
- wireless sensor
ASJC Scopus subject areas
- Biomedical Engineering