Revisiting the therapeutic time window dogma: successful thrombectomy 6 days after stroke onset

Pedro Aguilar-Salinas, Roberta Santos, Manuel F. Granja, Sabih Effendi, Eric Sauvageau, Ricardo Hanel, Amin Aghaebrahim

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Stroke is the leading cause of serious long-term disability in the USA. Recent clinical trials, DAWN and DEFUSE 3, have expanded the endovascular therapeutic time window which has been adopted by the American Heart Association stroke guideline. However, there continues to be a dilemma as to what is the best approach for patients who present beyond the time window set by these trials and the current guideline. The interval from arterial occlusion to completion of brain tissue infarction varies from patient to patient and depends on the actual time and also a physiological clock or a tissue time window. Offering endovascular treatment based solely on a rigid time criterion excludes patients who may have a clinical benefit because of potentially salvageable tissue. We present a case of a patient who underwent successful stroke thrombectomy 6 days after stroke onset.

Original languageEnglish (US)
Article number014039
JournalBMJ Case Reports
Volume2018
DOIs
StatePublished - 2018

Keywords

  • Ct Perfusion
  • Intervention
  • Stroke
  • Thrombectomy

ASJC Scopus subject areas

  • Medicine(all)

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