Retrograde Coronary Venous Ethanol Infusion for Ablation of Refractory Left Ventricular Summit Arrhythmias

Thomas Flautt; Miguel Valderrábano

doi:10.1016/j.ccep.2022.10.003

Retrograde Coronary Venous Ethanol Infusion for Ablation of Refractory Left Ventricular Summit Arrhythmias

Thomas Flautt, Miguel Valderrábano

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Chemical ablation using the transcoronary arterial system has a lengthy but arduous history. Although it has shown to be efficacious in controlling ventricular arrhythmias, safety concerns from cannulation of the coronary arterial system to unwanted ethanol downstream effects have limited transcoronary ethanol ablation (TCEA)'s use. Retrograde coronary venous ethanol ablation (RCVEA) has shown promising results. Although it appears to be in its infancy, RCVEA appears to be the future of chemical ablation in comparison to TCEA due to its increased safety and efficacy. Prospective randomized trial data is needed for this adjunctive treatment to radiofrequency ablation.

Original language	English (US)
Pages (from-to)	63-74
Number of pages	12
Journal	Cardiac Electrophysiology Clinics
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.ccep.2022.10.003
State	Published - Mar 2023

Keywords

Ablation
Alcohol
Annular vein
Heart Ventricles
Tachycardia, Ventricular
Prospective Studies
Ethanol
Humans
Arrhythmias, Cardiac/surgery
Catheter Ablation
Treatment Outcome

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1016/j.ccep.2022.10.003

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@article{27a95efafc9446a994bda00622ce594c,

title = "Retrograde Coronary Venous Ethanol Infusion for Ablation of Refractory Left Ventricular Summit Arrhythmias",

abstract = "Chemical ablation using the transcoronary arterial system has a lengthy but arduous history. Although it has shown to be efficacious in controlling ventricular arrhythmias, safety concerns from cannulation of the coronary arterial system to unwanted ethanol downstream effects have limited transcoronary ethanol ablation (TCEA)'s use. Retrograde coronary venous ethanol ablation (RCVEA) has shown promising results. Although it appears to be in its infancy, RCVEA appears to be the future of chemical ablation in comparison to TCEA due to its increased safety and efficacy. Prospective randomized trial data is needed for this adjunctive treatment to radiofrequency ablation.",

keywords = "Ablation, Alcohol, Annular vein, Heart Ventricles, Tachycardia, Ventricular, Prospective Studies, Ethanol, Humans, Arrhythmias, Cardiac/surgery, Catheter Ablation, Treatment Outcome",

author = "Thomas Flautt and Miguel Valderr{\'a}bano",

note = "Funding Information: This study was supported by the Charles Burnett III and Lois and Carl Davis Centennial Chair endowments (Houston, Texas, USA).",

year = "2023",

month = mar,

doi = "10.1016/j.ccep.2022.10.003",

language = "English (US)",

volume = "15",

pages = "63--74",

journal = "Cardiac Electrophysiology Clinics",

issn = "1877-9182",

publisher = "W.B. Saunders",

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}

TY - JOUR

T1 - Retrograde Coronary Venous Ethanol Infusion for Ablation of Refractory Left Ventricular Summit Arrhythmias

AU - Flautt, Thomas

AU - Valderrábano, Miguel

N1 - Funding Information: This study was supported by the Charles Burnett III and Lois and Carl Davis Centennial Chair endowments (Houston, Texas, USA).

PY - 2023/3

Y1 - 2023/3

N2 - Chemical ablation using the transcoronary arterial system has a lengthy but arduous history. Although it has shown to be efficacious in controlling ventricular arrhythmias, safety concerns from cannulation of the coronary arterial system to unwanted ethanol downstream effects have limited transcoronary ethanol ablation (TCEA)'s use. Retrograde coronary venous ethanol ablation (RCVEA) has shown promising results. Although it appears to be in its infancy, RCVEA appears to be the future of chemical ablation in comparison to TCEA due to its increased safety and efficacy. Prospective randomized trial data is needed for this adjunctive treatment to radiofrequency ablation.

AB - Chemical ablation using the transcoronary arterial system has a lengthy but arduous history. Although it has shown to be efficacious in controlling ventricular arrhythmias, safety concerns from cannulation of the coronary arterial system to unwanted ethanol downstream effects have limited transcoronary ethanol ablation (TCEA)'s use. Retrograde coronary venous ethanol ablation (RCVEA) has shown promising results. Although it appears to be in its infancy, RCVEA appears to be the future of chemical ablation in comparison to TCEA due to its increased safety and efficacy. Prospective randomized trial data is needed for this adjunctive treatment to radiofrequency ablation.

KW - Ablation

KW - Alcohol

KW - Annular vein

KW - Heart Ventricles

KW - Tachycardia, Ventricular

KW - Prospective Studies

KW - Ethanol

KW - Humans

KW - Arrhythmias, Cardiac/surgery

KW - Catheter Ablation

KW - Treatment Outcome

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UR - http://www.scopus.com/inward/citedby.url?scp=85146082601&partnerID=8YFLogxK

U2 - 10.1016/j.ccep.2022.10.003

DO - 10.1016/j.ccep.2022.10.003

M3 - Review article

C2 - 36774138

AN - SCOPUS:85146082601

SN - 1877-9182

VL - 15

SP - 63

EP - 74

JO - Cardiac Electrophysiology Clinics

JF - Cardiac Electrophysiology Clinics

IS - 1

ER -

Retrograde Coronary Venous Ethanol Infusion for Ablation of Refractory Left Ventricular Summit Arrhythmias

Abstract

Keywords

ASJC Scopus subject areas

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