Retrogeniculate Lesion of the Visual Pathways: Retinal Optical Coherence Tomography Angiography Shows Evidence of Transsynaptic Retrograde Degeneration

Francesco Pellegrini, Emanuela Interlandi, Francesco Pichi, Andrew G. Lee

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Transsynaptic retrograde degeneration (TSRD) of the visual pathways is the loss of retinal ganglion cells occurring upstream from a posterior visual pathway lesion. We present a case of a 54-year-old woman with an epidermoid cyst at the right temporo-occipital junction, in whom retinal optical coherence tomography angiography showed a reduction of the superficial retinal capillary density consistent with TSRD. While this reduction has been described in chronic optic neuropathies and pregeniculate lesions, to our knowledge, this is the first case report showing how a reduction in the superficial retinal capillary density occurs also for a postgeniculate lesion.

Original languageEnglish (US)
Pages (from-to)114-117
Number of pages4
JournalNeuro-Ophthalmology
Volume44
Issue number2
DOIs
StateE-pub ahead of print - Jul 12 2020

Keywords

  • Optical coherence tomography angiography
  • superficial capillary plexus
  • transsynaptic retrograde degeneration

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

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