Retinoblastoma is a rare primary intraocular malignancy. Presentation in the neonatal period is not common. With improved genetic testing, screening of the unborn child and neonate is taking on a greater role in the management of these patients. Treatment of retinoblastoma in the neonate is complex and requires a multidisciplinary and highly individualized approach. If possible, focal modalities should be used and external beam radiation avoided. Systemic intravenous chemotherapy may be necessary with regimens including carboplatin, vincristine and etoposide. Such cases are best managed by specialist centers with access to experts in oncology, ophthalmology, radiation therapy, genetics, pathology and anesthesia.
- Periocular chemotherapy
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health