Respiratory motor training and neuromuscular plasticity in patients with chronic obstructive pulmonary disease: A pilot study

Alexander V. Ovechkin, Dimitry G. Sayenko, Elena N. Ovechkina, Sevda C. Aslan, Teresa Pitts, Rodney J. Folz

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The objective of this study was to examine the feasibility of a full-scale investigation of the neurophysiological mechanisms of COPD-induced respiratory neuromuscular control deficits. Characterization of respiratory single- and multi-muscle activation patterns using surface electromyography (sEMG) were assessed along with functional measures at baseline and following 21 ± 2 (mean ± SD) sessions of respiratory motor training (RMT) performed during a one-month period in four patients with GOLD stage II or III COPD. Pre-training, the individuals with COPD showed significantly increased (p < 0.05) overall respiratory muscle activity and disorganized multi-muscle activation patterns in association with lowered spirometrical measures and decreased fast- and slow-twitch fiber activity as compared to healthy controls (N = 4). Following RMT, functional and respiratory sEMG activation outcomes during quite breathing and forced expiratory efforts were improved suggesting that functional improvements, induced by task-specific RMT, are evidence respiratory neuromuscular networks re-organization.

Original languageEnglish (US)
Pages (from-to)59-64
Number of pages6
JournalRespiratory Physiology and Neurobiology
Volume229
DOIs
StatePublished - Jul 15 2016

Keywords

  • Chronic obstructive pulmonary disease
  • EMG
  • Electromyography
  • Respiratory motor function
  • Respiratory muscles
  • Respiratory training

ASJC Scopus subject areas

  • Neuroscience(all)
  • Physiology
  • Pulmonary and Respiratory Medicine

Fingerprint Dive into the research topics of 'Respiratory motor training and neuromuscular plasticity in patients with chronic obstructive pulmonary disease: A pilot study'. Together they form a unique fingerprint.

Cite this