Residual Kidney Function: Implications in the Era of Personalized Medicine

Tariq Shafi; Surekha Mullangi; Stephanie M. Toth-Manikowski; Seungyoung Hwang; Wieneke M. Michels

doi:10.1111/sdi.12587

Residual Kidney Function: Implications in the Era of Personalized Medicine

Tariq Shafi, Surekha Mullangi, Stephanie M. Toth-Manikowski, Seungyoung Hwang, Wieneke M. Michels

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The association of residual kidney function (RKF) with improved outcomes in peritoneal dialysis and hemodialysis patients is now widely recognized. RKF provides substantial volume and solute clearance even after dialysis initiation. In particular, RKF provides clearance of nonurea solutes, many of which are potential uremic toxins and not effectively removed by conventional hemodialysis. The presence of RKF provides a distinct advantage to incident dialysis patients and is an opportunity for nephrologists to individualize dialysis treatments tailored to their patients’ unique solute, volume, and quality of life needs. The benefits of RKF present the opportunity to personalize the management of uremia.

Original language	English (US)
Pages (from-to)	241-245
Number of pages	5
Journal	Seminars in Dialysis
Volume	30
Issue number	3
DOIs	https://doi.org/10.1111/sdi.12587
State	Published - May 1 2017

ASJC Scopus subject areas

Nephrology

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abstract = "The association of residual kidney function (RKF) with improved outcomes in peritoneal dialysis and hemodialysis patients is now widely recognized. RKF provides substantial volume and solute clearance even after dialysis initiation. In particular, RKF provides clearance of nonurea solutes, many of which are potential uremic toxins and not effectively removed by conventional hemodialysis. The presence of RKF provides a distinct advantage to incident dialysis patients and is an opportunity for nephrologists to individualize dialysis treatments tailored to their patients{\textquoteright} unique solute, volume, and quality of life needs. The benefits of RKF present the opportunity to personalize the management of uremia.",

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Residual Kidney Function: Implications in the Era of Personalized Medicine

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