TY - JOUR
T1 - Residual Kidney Function
T2 - Implications in the Era of Personalized Medicine
AU - Shafi, Tariq
AU - Mullangi, Surekha
AU - Toth-Manikowski, Stephanie M.
AU - Hwang, Seungyoung
AU - Michels, Wieneke M.
N1 - Publisher Copyright:
© 2017 Wiley Periodicals, Inc.
PY - 2017/5/1
Y1 - 2017/5/1
N2 - The association of residual kidney function (RKF) with improved outcomes in peritoneal dialysis and hemodialysis patients is now widely recognized. RKF provides substantial volume and solute clearance even after dialysis initiation. In particular, RKF provides clearance of nonurea solutes, many of which are potential uremic toxins and not effectively removed by conventional hemodialysis. The presence of RKF provides a distinct advantage to incident dialysis patients and is an opportunity for nephrologists to individualize dialysis treatments tailored to their patients’ unique solute, volume, and quality of life needs. The benefits of RKF present the opportunity to personalize the management of uremia.
AB - The association of residual kidney function (RKF) with improved outcomes in peritoneal dialysis and hemodialysis patients is now widely recognized. RKF provides substantial volume and solute clearance even after dialysis initiation. In particular, RKF provides clearance of nonurea solutes, many of which are potential uremic toxins and not effectively removed by conventional hemodialysis. The presence of RKF provides a distinct advantage to incident dialysis patients and is an opportunity for nephrologists to individualize dialysis treatments tailored to their patients’ unique solute, volume, and quality of life needs. The benefits of RKF present the opportunity to personalize the management of uremia.
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U2 - 10.1111/sdi.12587
DO - 10.1111/sdi.12587
M3 - Article
C2 - 28264139
AN - SCOPUS:85014519396
VL - 30
SP - 241
EP - 245
JO - Seminars in Dialysis
JF - Seminars in Dialysis
SN - 0894-0959
IS - 3
ER -