Reprinted Article "pathophysiology of vein graft failure: A review"

M. G. Davies; P. O. Hagen

doi:10.1016/j.ejvs.2011.06.013

Reprinted Article "pathophysiology of vein graft failure: A review"

M. G. Davies, P. O. Hagen

Houston Methodist

Research output: Contribution to journal › Review article › peer-review

24 Scopus citations

Abstract

Vein bypass grafting is an integral component of cardiovascular surgical practice for both arterial and venous diseases. However, many of these grafts will eventually fail due to either intrinsic or extrinsic causes. This review examines the current understanding and knowledge of venous histology, vein graft pathology and the associated endothelial and smooth muscle cell physiology and pharmacology. In addition, the status of research on the therapeutic control of vein graft intimal hyperplasia and accelerated atherosclerosis is assessed.

Original language	English (US)
Pages (from-to)	S19-S29
Journal	European Journal of Vascular and Endovascular Surgery
Volume	42
Issue number	SUPPL.1
DOIs	https://doi.org/10.1016/j.ejvs.2011.06.013
State	Published - Sep 2011

Keywords

Atherosclerosis
Failure
Intimal hyperplasia
Smooth muscle cell endothelium
Vein
Vein graft

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Surgery

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10.1016/j.ejvs.2011.06.013

Cite this

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title = "Reprinted Article {"}pathophysiology of vein graft failure: A review{"}",

abstract = "Vein bypass grafting is an integral component of cardiovascular surgical practice for both arterial and venous diseases. However, many of these grafts will eventually fail due to either intrinsic or extrinsic causes. This review examines the current understanding and knowledge of venous histology, vein graft pathology and the associated endothelial and smooth muscle cell physiology and pharmacology. In addition, the status of research on the therapeutic control of vein graft intimal hyperplasia and accelerated atherosclerosis is assessed.",

keywords = "Atherosclerosis, Failure, Intimal hyperplasia, Smooth muscle cell endothelium, Vein, Vein graft",

author = "Davies, {M. G.} and Hagen, {P. O.}",

note = "Funding Information: Grant Support: U.S. Public Health Service HL 15448. American Heart Association (NC Affiliate) NC 92-GB-31 Mark G. Davies is supported by a N.I.H. Fogarty International Research Fellowship (TW 04810) and holds a Royal College of Surgeons in Ireland Surgical Travelling Fellowship and a Trinity College Dublin Postgraduate Scholarship.",

year = "2011",

month = sep,

doi = "10.1016/j.ejvs.2011.06.013",

language = "English (US)",

volume = "42",

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AU - Hagen, P. O.

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PY - 2011/9

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N2 - Vein bypass grafting is an integral component of cardiovascular surgical practice for both arterial and venous diseases. However, many of these grafts will eventually fail due to either intrinsic or extrinsic causes. This review examines the current understanding and knowledge of venous histology, vein graft pathology and the associated endothelial and smooth muscle cell physiology and pharmacology. In addition, the status of research on the therapeutic control of vein graft intimal hyperplasia and accelerated atherosclerosis is assessed.

AB - Vein bypass grafting is an integral component of cardiovascular surgical practice for both arterial and venous diseases. However, many of these grafts will eventually fail due to either intrinsic or extrinsic causes. This review examines the current understanding and knowledge of venous histology, vein graft pathology and the associated endothelial and smooth muscle cell physiology and pharmacology. In addition, the status of research on the therapeutic control of vein graft intimal hyperplasia and accelerated atherosclerosis is assessed.

KW - Atherosclerosis

KW - Failure

KW - Intimal hyperplasia

KW - Smooth muscle cell endothelium

KW - Vein

KW - Vein graft

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Reprinted Article "pathophysiology of vein graft failure: A review"

Abstract

Keywords

ASJC Scopus subject areas

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