Renal cell carcinoma with calcium oxalate deposition: A distinct type of renal cell carcinoma within the spectrum of renal neoplasms associated with acquired cystic kidney disease

Cystic changes may develop in kidneys of patients with end-stage renal disease treated with long-term dialysis, a condition termed acquired cystic kidney disease. Renal neoplasms frequently develop in this process and they display a wide morphologic spectrum encompassing all of the usual renal tumors. However, one histologic type among them, characterized by tumoral deposition of calcium oxalate crystals, is seen only in the context of acquired cystic kidney disease. This communication reports one such tumor and reviews the clinicopathologic features of acquired cystic kidney disease and the renal neoplasms associated with this condition, with special emphasis on the particular renal cell carcinoma associated with tumoral calcium oxalate deposition.