Renal amyloidosis characterized by abnormally thick fibrils

Yasuji Yoshikawa, Luan Truong, Carlos Mattioli, Joiner Cartwright

Research output: Contribution to journalArticlepeer-review


A renal biopsy of a 57-year-old man with nephrotic syndrome revealed marked glomerular deposition of Congo red-positive, birefringent material characteristic for amyloid. Ultrastructurally, however, this material is composed of nonbranching, haphazardly arranged fibrils of approximately three times the thickness of typical amyloid fibrils. To our knowledge, there has been no report of such a finding, and this unique case enlarges the morphologic spectrum of renal fibrillosis.

Original languageEnglish (US)
Pages (from-to)868-871
Number of pages4
JournalHuman Pathology
Issue number8
StatePublished - Aug 1990


  • amyloidosis
  • Congo red stain
  • immunotactoid glomerulopathy
  • kidney

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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