TY - JOUR
T1 - Relation of serum uric acid with metabolic risk factors in asymptomatic middle-aged Brazilian men
AU - Desai, Milind Y.
AU - Santos, Raul D.
AU - Dalal, Darshan
AU - Carvalho, Jose A.M.
AU - Martin, Don R.
AU - Flynn, John A.
AU - Nasir, Khurram
AU - Blumenthal, Roger S.
N1 - Funding Information:
This study was supported in part by an unrestricted educational grant from the Maryland Athletic Club Charitable Foundation, Timonium, Maryland.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2005/4/1
Y1 - 2005/4/1
N2 - This study in 352 asymptomatic middle-aged Brazilian men demonstrated that serum uric acid increases linearly with an increasing number (0 to ≥3) of metabolic risk factors (5.78 ± 1.1, 6.14 ± 1.0, 6.27 ± 1.1, and 6.79 ± 1.3, p <0.001). In patients who had ≥3 metabolic risk factors, there was a higher prevalence of serum uric acid in the highest quartile (7.2 to 10.3 mg/dl) than in the lowest quartile (2.6 to 5.4 mg/dl, 35% vs 12%, p <0.001). Mean serum levels of uric acid were higher in those who had an abnormal ratio of ≥3 for triglyceride to high-density lipoprotein (suggesting insulin resistance) than in those who had a normal ratio (6.6 ± 1.2 vs 5.87 ± 1 mg/dl, p <0.001).
AB - This study in 352 asymptomatic middle-aged Brazilian men demonstrated that serum uric acid increases linearly with an increasing number (0 to ≥3) of metabolic risk factors (5.78 ± 1.1, 6.14 ± 1.0, 6.27 ± 1.1, and 6.79 ± 1.3, p <0.001). In patients who had ≥3 metabolic risk factors, there was a higher prevalence of serum uric acid in the highest quartile (7.2 to 10.3 mg/dl) than in the lowest quartile (2.6 to 5.4 mg/dl, 35% vs 12%, p <0.001). Mean serum levels of uric acid were higher in those who had an abnormal ratio of ≥3 for triglyceride to high-density lipoprotein (suggesting insulin resistance) than in those who had a normal ratio (6.6 ± 1.2 vs 5.87 ± 1 mg/dl, p <0.001).
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U2 - 10.1016/j.amjcard.2004.12.013
DO - 10.1016/j.amjcard.2004.12.013
M3 - Article
C2 - 15781018
AN - SCOPUS:15244356856
VL - 95
SP - 865
EP - 868
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 7
ER -