Relation of an elevated white blood cell count after percutaneous coronary intervention to long-term mortality

Vivek Rajagopal; Hitinder S. Gurm; Deepak L. Bhatt; A. Michael Lincoff; James E. Tcheng; Dean J. Kereiakes; Neal S. Kleiman; Gang Jia; Eric J. Topol

doi:10.1016/j.amjcard.2004.03.060

Relation of an elevated white blood cell count after percutaneous coronary intervention to long-term mortality

Vivek Rajagopal, Hitinder S. Gurm, Deepak L. Bhatt, A. Michael Lincoff, James E. Tcheng, Dean J. Kereiakes, Neal S. Kleiman, Gang Jia, Eric J. Topol

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26 Scopus citations

Abstract

Increased inflammatory markers are associated with a poor prognosis after percutaneous coronary intervention. Leukocytes play a key role in inflammation, and an increase in white blood cell (WBC) counts is a nonspecific marker of inflammation. In patients undergoing percutaneous coronary intervention, baseline WBC counts independently predict long-term mortality. In a pooled cohort of patients from the Evaluation of c7E3 for the Prevention of Ischemic Complications (EPIC), the Evaluation in PTCA to Improve Long-term Outcome with abciximab Glycoprotein IIb/IIIa blockade (EPILOG), and Evaluation of Platelet IIb/IIIa inhibitor for STENTing (EPISTENT) trials, postprocedural WBC counts were also found to be an independent predictor of long-term mortality.

Original language	English (US)
Pages (from-to)	190-192
Number of pages	3
Journal	American Journal of Cardiology
Volume	94
Issue number	2
DOIs	https://doi.org/10.1016/j.amjcard.2004.03.060
State	Published - Jul 15 2004

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.amjcard.2004.03.060

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title = "Relation of an elevated white blood cell count after percutaneous coronary intervention to long-term mortality",

abstract = "Increased inflammatory markers are associated with a poor prognosis after percutaneous coronary intervention. Leukocytes play a key role in inflammation, and an increase in white blood cell (WBC) counts is a nonspecific marker of inflammation. In patients undergoing percutaneous coronary intervention, baseline WBC counts independently predict long-term mortality. In a pooled cohort of patients from the Evaluation of c7E3 for the Prevention of Ischemic Complications (EPIC), the Evaluation in PTCA to Improve Long-term Outcome with abciximab Glycoprotein IIb/IIIa blockade (EPILOG), and Evaluation of Platelet IIb/IIIa inhibitor for STENTing (EPISTENT) trials, postprocedural WBC counts were also found to be an independent predictor of long-term mortality.",

author = "Vivek Rajagopal and Gurm, {Hitinder S.} and Bhatt, {Deepak L.} and Lincoff, {A. Michael} and Tcheng, {James E.} and Kereiakes, {Dean J.} and Kleiman, {Neal S.} and Gang Jia and Topol, {Eric J.}",

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AU - Rajagopal, Vivek

AU - Gurm, Hitinder S.

AU - Bhatt, Deepak L.

AU - Lincoff, A. Michael

AU - Tcheng, James E.

AU - Kereiakes, Dean J.

AU - Kleiman, Neal S.

AU - Jia, Gang

AU - Topol, Eric J.

PY - 2004/7/15

Y1 - 2004/7/15

N2 - Increased inflammatory markers are associated with a poor prognosis after percutaneous coronary intervention. Leukocytes play a key role in inflammation, and an increase in white blood cell (WBC) counts is a nonspecific marker of inflammation. In patients undergoing percutaneous coronary intervention, baseline WBC counts independently predict long-term mortality. In a pooled cohort of patients from the Evaluation of c7E3 for the Prevention of Ischemic Complications (EPIC), the Evaluation in PTCA to Improve Long-term Outcome with abciximab Glycoprotein IIb/IIIa blockade (EPILOG), and Evaluation of Platelet IIb/IIIa inhibitor for STENTing (EPISTENT) trials, postprocedural WBC counts were also found to be an independent predictor of long-term mortality.

AB - Increased inflammatory markers are associated with a poor prognosis after percutaneous coronary intervention. Leukocytes play a key role in inflammation, and an increase in white blood cell (WBC) counts is a nonspecific marker of inflammation. In patients undergoing percutaneous coronary intervention, baseline WBC counts independently predict long-term mortality. In a pooled cohort of patients from the Evaluation of c7E3 for the Prevention of Ischemic Complications (EPIC), the Evaluation in PTCA to Improve Long-term Outcome with abciximab Glycoprotein IIb/IIIa blockade (EPILOG), and Evaluation of Platelet IIb/IIIa inhibitor for STENTing (EPISTENT) trials, postprocedural WBC counts were also found to be an independent predictor of long-term mortality.

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Relation of an elevated white blood cell count after percutaneous coronary intervention to long-term mortality

Abstract

ASJC Scopus subject areas

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