Relation of an elevated white blood cell count after percutaneous coronary intervention to long-term mortality

Vivek Rajagopal, Hitinder S. Gurm, Deepak L. Bhatt, A. Michael Lincoff, James E. Tcheng, Dean J. Kereiakes, Neal S. Kleiman, Gang Jia, Eric J. Topol

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Increased inflammatory markers are associated with a poor prognosis after percutaneous coronary intervention. Leukocytes play a key role in inflammation, and an increase in white blood cell (WBC) counts is a nonspecific marker of inflammation. In patients undergoing percutaneous coronary intervention, baseline WBC counts independently predict long-term mortality. In a pooled cohort of patients from the Evaluation of c7E3 for the Prevention of Ischemic Complications (EPIC), the Evaluation in PTCA to Improve Long-term Outcome with abciximab Glycoprotein IIb/IIIa blockade (EPILOG), and Evaluation of Platelet IIb/IIIa inhibitor for STENTing (EPISTENT) trials, postprocedural WBC counts were also found to be an independent predictor of long-term mortality.

Original languageEnglish (US)
Pages (from-to)190-192
Number of pages3
JournalAmerican Journal of Cardiology
Volume94
Issue number2
DOIs
StatePublished - Jul 15 2004

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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