TY - JOUR
T1 - Relapsing polychondritis
AU - Asadi, Arash K.
PY - 2003
Y1 - 2003
N2 - A 57-year-old man presented with a 2-year history of (1) recurrent swelling of the ears that spared his earlobes and (2) migratory arthralgias. A biopsy specimen of the ear showed a perichondrial infiltrate of lymphocytes, plasma cells, and a few neutrophils. There were acellular foci of underlying cartilage. Relapsing polychondritis is characterized by recurrent inflammation and eventual destruction of cartilaginous tissues, primarily affecting the ears, nose, respiratory tract, and eyes. The condition, which is associated with autoimmunity against type II collagen, has a chronic, relapsing-and-remitting course that can be life-threatening. Treatments include a variety of anti-inflammatory and anti-neutrophilic agents, and the prognosis is variable and depends on which organ systems are involved and the response to therapy.
AB - A 57-year-old man presented with a 2-year history of (1) recurrent swelling of the ears that spared his earlobes and (2) migratory arthralgias. A biopsy specimen of the ear showed a perichondrial infiltrate of lymphocytes, plasma cells, and a few neutrophils. There were acellular foci of underlying cartilage. Relapsing polychondritis is characterized by recurrent inflammation and eventual destruction of cartilaginous tissues, primarily affecting the ears, nose, respiratory tract, and eyes. The condition, which is associated with autoimmunity against type II collagen, has a chronic, relapsing-and-remitting course that can be life-threatening. Treatments include a variety of anti-inflammatory and anti-neutrophilic agents, and the prognosis is variable and depends on which organ systems are involved and the response to therapy.
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U2 - 10.5070/d33kd3r1xd
DO - 10.5070/d33kd3r1xd
M3 - Article
C2 - 14594576
AN - SCOPUS:3042569772
SN - 1087-2108
VL - 9
SP - 9
EP - 11
JO - Dermatology Online Journal
JF - Dermatology Online Journal
IS - 4
ER -