Regurgitation quantification using 3D PISA in volume echocardiography

Leo Grady, Saurabh Datta, Oliver Kutter, Christophe Duong, Wolfgang Wein, Stephen H. Little, Stephen R. Igo, Shizhen Liu, Mani Vannan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

37 Scopus citations

Abstract

We present the first system for measurement of proximal isovelocity surface area (PISA) on a 3D ultrasound acquisition using modified ultrasound hardware, volumetric image segmentation and a simple efficient workflow. Accurate measurement of the PISA in 3D flow through a valve is an emerging method for quantitatively assessing cardiac valve regurgitation and function. Current state of the art protocols for assessing regurgitant flow require laborious and time consuming user interaction with the data, where a precise execution is crucial for an accurate diagnosis. We propose a new improved 3D PISA workflow that is initialized interactively with two points, followed by fully automatic segmentation of the valve annulus and isovelocity surface area computation. Our system is first validated against several in vitro phantoms to verify the calculations of surface area, orifice area and regurgitant flow. Finally, we use our system to compare orifice area calculations obtained from in vivo patient imaging measurements to an independent measurement and then use our system to successfully classify patients into mild-moderate regurgitation and moderate-severe regurgitation categories.

Original languageEnglish
Title of host publicationLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Pages512-519
Number of pages8
Volume6893 LNCS
EditionPART 3
DOIs
StatePublished - Dec 1 2011
Event14th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2011 - Toronto, ON, Canada
Duration: Sep 18 2011Sep 22 2011

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 3
Volume6893 LNCS
ISSN (Print)03029743
ISSN (Electronic)16113349

Other

Other14th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2011
CountryCanada
CityToronto, ON
Period9/18/119/22/11

ASJC Scopus subject areas

  • Computer Science(all)
  • Theoretical Computer Science

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