Regulatory T cells and toll-like receptors in cancer therapy

Research output: Contribution to journalReview article

31 Scopus citations

Abstract

T regulatory (Treg) cells that suppress immune responses may limit the efficiency of cancer immunotherapy. Recent findings indicate that Toll-like receptors (TLR) directly regulate the suppressive activity of Treg cells. Linking TLR signaling to the functional control of Treg cells may offer new opportunities to improve the outcome of cancer immunotherapy by coadminstration of certain TLR ligands.

Original languageEnglish (US)
Pages (from-to)4987-4990
Number of pages4
JournalCancer research
Volume66
Issue number10
DOIs
StatePublished - May 15 2006

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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