Regression of left ventricular hypertrophy: Are there preferred drugs?

Joseph A. Diamond, Robert A. Phillips

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

The presence of left ventricular hypertrophy (LVH) confers markedly increased risk of cardiovascular morbidity and mortality in patients with hypertension. Regression of left ventricular (LV) mass with antihypertensive therapy is associated with reduction in cardiovascular events. In studies based on monotherapy, among the classes of antihypertensive drugs that have been adequately tested, diuretics and angiotensin-converting enzyme inhibitors appear to be the most effective agents for reducing LV mass. New avenues of research, based on combination antihypertensive therapy and on a more sophisticated understanding of the molecular mechanisms of LVH, may yield new pharmacologic approaches to regressing LV mass.

Original languageEnglish (US)
Pages (from-to)368-371
Number of pages4
JournalCurrent Hypertension Reports
Volume5
Issue number5
DOIs
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Internal Medicine

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