Abstract
We investigated the adoptive transfer of immunity to herpes simplex virus (HSV) in 61 recipients of T-cell-depleted marrow allografts. Up to 3 months after bone marrow transplantation (BMT), high titres of HSV antibody (Ab) are passively acquired from blood products. This antibody has a half-life of 40.3 days, so that determination of recipient immunity to HSV cannot be made during the early post-transplant period. By 4 months after the allograft, seronegative recipients of seronegative donors had near-background levels of HSV Ab. Seropositive recipients,
Original language | English (US) |
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Pages (from-to) | 93-99 |
Number of pages | 7 |
Journal | Journal of Medical Virology |
Volume | 23 |
Issue number | 1 |
DOIs | |
State | Published - Sep 1987 |
Keywords
- T‐cell depletion
- immunity transfer
- marrow transplant
- viral infections
ASJC Scopus subject areas
- Virology
- Infectious Diseases