TY - JOUR
T1 - Recurrent thrombotic thrombocytopenic purpura in early pregnancy
T2 - Effect of uterine evacuation
AU - Natelson, Ethan
AU - White, Dezra
PY - 1985/1/1
Y1 - 1985/1/1
N2 - A 29-year-old woman developed thrombotic thrombocytopenic purpura on two occasions, each with onset at about the 13th week of gestation. Despite therapy during each episode with corticosteroids, platelet aggregation-modifying agents and repeated plasmapheresis, she experienced only transient improvement. In both instances, however, prompt hematologic recovery followed evacuation of the uterus. During an 18-month interval between pregnancies, her blood count remained normal and she continues in remission. The authors suggest that when thrombotic thrombocytopenic purpura appears in early pregnancy and its response to conventional management is minimal, immediate evacuation of the uterus may be an effective therapeutic alternative.
AB - A 29-year-old woman developed thrombotic thrombocytopenic purpura on two occasions, each with onset at about the 13th week of gestation. Despite therapy during each episode with corticosteroids, platelet aggregation-modifying agents and repeated plasmapheresis, she experienced only transient improvement. In both instances, however, prompt hematologic recovery followed evacuation of the uterus. During an 18-month interval between pregnancies, her blood count remained normal and she continues in remission. The authors suggest that when thrombotic thrombocytopenic purpura appears in early pregnancy and its response to conventional management is minimal, immediate evacuation of the uterus may be an effective therapeutic alternative.
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M3 - Article
C2 - 4040623
AN - SCOPUS:0022353961
SN - 0029-7844
VL - 66
SP - 54S-56S
JO - Obstetrics and Gynecology
JF - Obstetrics and Gynecology
IS - 3
ER -