Recurrent hepatic lymphangiomatosis after orthotopic liver transplantation

Seong H. Ra, Robert F. Bradley, Michael C. Fishbein, Ronald W. Busuttil, David S.K. Lu, Charles R. Lassman

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Hepatic lymphangiomatosis is a rare disease characterized by an abnormal lymphatic proliferation involving the liver alone, liver and spleen, or multiple organs. Hepatic lymphangiomatosis becomes symptomatic secondary to compression or replacement of the normal parenchyma, which can lead to liver failure. Resection and orthotopic liver transplantation (OLT) can be used as treatment for this disease. We herein describe a 42-year-old female who had undergone successful OLT for hepatic lymphangiomatosis with recurrent disease detected 19 yr later in the transplanted liver. This is, to our knowledge, the first described case of recurrent hepatic lymphangiomatosis after OLT. In conclusion, we discuss the clinical, radiologic, pathologic, and immunohistochemical findings and review other reported cases of hepatic lymphangiomatosis that have undergone OLT.

Original languageEnglish (US)
Pages (from-to)1593-1597
Number of pages5
JournalLiver Transplantation
Issue number11
StatePublished - Nov 2007

ASJC Scopus subject areas

  • Surgery
  • Hepatology
  • Transplantation


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