3 Scopus citations

Abstract

Mesenchymal stem cells (MSCs) are used as therapeutic agents for the treatment of a wide spectrum of diseases, as well as for the regeneration and healing of burns and wounds. MSCs have an immunomodulatory effect and influence the phenotype and functions of immune cells, including macrophages, which in turn prime and license the MSCs. We discuss the new findings on the feedback loop between MSCs and macrophages and its consequences on the outcome of MSC therapies.

Original languageEnglish (US)
Pages (from-to)465-469
Number of pages5
JournalInternational Journal of Developmental Biology
Volume64
Issue number11-12
DOIs
StatePublished - 2020

Keywords

  • Immunomodulation
  • MSC
  • MSC therapy
  • Macrophage
  • Mesenchymal stem cell

ASJC Scopus subject areas

  • Embryology
  • Developmental Biology

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