Recent Progress of Microfluidics in Translational Applications

Zongbin Liu, Xin Han, Lidong Qin

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Microfluidics, featuring microfabricated structures, is a technology for manipulating fluids at the micrometer scale. The small dimension and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design is presented. The potential future developments in the translational microfluidics field are also discussed. The small dimensions and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and thus show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications is presented, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design. The potential challenges of the current microfluidics platforms for future translational applications are also discussed.

Original languageEnglish (US)
Pages (from-to)871-888
Number of pages18
JournalAdvanced Healthcare Materials
Volume5
Issue number8
DOIs
StatePublished - Apr 20 2016

Keywords

  • Cellular analysis
  • Chip-based material delivery
  • Microfluidics
  • Molecular analysis
  • Organ-on-a-chip

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Pharmaceutical Science

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