TY - JOUR
T1 - Recent Progress of Microfluidics in Translational Applications
AU - Liu, Zongbin
AU - Han, Xin
AU - Qin, Lidong
N1 - Funding Information:
The authors are grateful for funding from NIH-R01CA180083, NIHU54CA143837, NIH-R01DA035868, NIH-R56AG049714, NIH/NCI (1R21CA191179-01A1) and Golfers against Cancer Foundation.
Funding Information:
The authors are grateful for funding from NIH-R01CA180083, NIHU54CA143837, NIH-R01DA035868, NIH-R56AG049714, NIH/NCI (1R21CA191179-01A1) and Golfers against Cancer Foundation.
Publisher Copyright:
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
PY - 2016/4/20
Y1 - 2016/4/20
N2 - Microfluidics, featuring microfabricated structures, is a technology for manipulating fluids at the micrometer scale. The small dimension and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design is presented. The potential future developments in the translational microfluidics field are also discussed. The small dimensions and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and thus show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications is presented, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design. The potential challenges of the current microfluidics platforms for future translational applications are also discussed.
AB - Microfluidics, featuring microfabricated structures, is a technology for manipulating fluids at the micrometer scale. The small dimension and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design is presented. The potential future developments in the translational microfluidics field are also discussed. The small dimensions and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and thus show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications is presented, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design. The potential challenges of the current microfluidics platforms for future translational applications are also discussed.
KW - Cellular analysis
KW - Chip-based material delivery
KW - Microfluidics
KW - Molecular analysis
KW - Organ-on-a-chip
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U2 - 10.1002/adhm.201600009
DO - 10.1002/adhm.201600009
M3 - Article
C2 - 27091777
AN - SCOPUS:84962529190
SN - 2192-2640
VL - 5
SP - 871
EP - 888
JO - Advanced Healthcare Materials
JF - Advanced Healthcare Materials
IS - 8
ER -