Abstract
Microfluidics, featuring microfabricated structures, is a technology for manipulating fluids at the micrometer scale. The small dimension and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design is presented. The potential future developments in the translational microfluidics field are also discussed. The small dimensions and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and thus show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications is presented, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design. The potential challenges of the current microfluidics platforms for future translational applications are also discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 871-888 |
| Number of pages | 18 |
| Journal | Advanced Healthcare Materials |
| Volume | 5 |
| Issue number | 8 |
| DOIs | |
| State | Published - Apr 20 2016 |
Keywords
- Cellular analysis
- Chip-based material delivery
- Microfluidics
- Molecular analysis
- Organ-on-a-chip
ASJC Scopus subject areas
- Biomaterials
- Biomedical Engineering
- Pharmaceutical Science