Rapid response of emotional incontinence to selective serotonin reuptake inhibitors

Ziad Nahas, Kimberly A. Arlinghaus, Kathryn J. Kotrla, Rebecca R. Clearman, Mark S. George

Research output: Contribution to journalArticlepeer-review

77 Scopus citations


Emotional incontinence (EI) is a perturbing condition characterized by uncontrollable outbursts of exaggerated, involuntary facial expressions and pathological crying or laughter. There is increasing evidence that serotonergic neurotransmission may be damaged in EI. The authors report 4 pathological crying cases (3 poststroke and 1 with multiple sclerosis) and 1 case of pathological laughter after traumatic brain injury. EI improved dramatically with three different selective serotonin reuptake inhibitors (fluoxetine, sertraline, and paroxetine) in the context of these different CNS diseases.

Original languageEnglish (US)
Pages (from-to)453-455
Number of pages3
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Issue number4
StatePublished - Jan 1 1998

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health


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