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Radiation Therapy for Solitary Fibrous Tumor of the Orbit

Agni Kakouri, Kaveh Vahdani, Matthew J. Debnam, Ashleigh B. Guadagnolo, Geoffrey E. Rose, David Verity, Tracy Lu, Bita Esmaeli

Research output: Contribution to journalArticlepeer-review

Abstract

Solitary fibrous tumor, formerly also referred to as hemangiopericytoma, is a fibroblastic mesenchymal neoplasm of the orbit that rarely metastasizes but has a propensity for local recurrence. The authors describe 5 cases of orbital solitary fibrous tumors that were treated with radiation. In 3 patients, radiation therapy was given in the neoadjuvant setting prior to surgery. In the remaining 2 patients, radiation was used palliatively in patients who declined surgery. In 4 of 5 cases, a measurable reduction in the size of the orbital mass was observed in response to radiation therapy; however, long-term adverse effects of radiation may not yet be evident, given the relatively short follow-up period for some of the patients in this report.

Original languageEnglish (US)
Pages (from-to)e63-e68
JournalOphthalmic Plastic and Reconstructive Surgery
Volume42
Issue number2
DOIs
StatePublished - Apr 1 2026

Keywords

  • Humans
  • Orbital Neoplasms/radiotherapy
  • Solitary Fibrous Tumors/radiotherapy
  • Female
  • Male
  • Middle Aged
  • Aged
  • Adult
  • Tomography, X-Ray Computed
  • Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

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