Racial/Ethnic Disparities in the Burden of HIV/Cervical Cancer Comorbidity and Related In-hospital Mortality in the USA

Hamisu Salihu, Deepa Dongarwar, Chioma A. Ikedionwu, Andrea Shelton, China M. Jenkins, Collins Onyenaka, Creaque Charles, Hongmei Wang, Inyang Osemene, Kiydra J. Harris, Manvir Kaur, Monica Rasmus, Ololade Awosemo, Shirlette Milton, Sonnice Estill, Tolulope Adebusuyi, Xiuqing Gao, Ya Fatou N. Mbye, Yuan Chen, Omonike A. Olaleye

Research output: Contribution to journalArticle

Abstract

Objective: The purpose of this study was to determine whether cervical cancer is a risk factor for early mortality among women with HIV and whether racial/ethnic disparity predicted in-hospital death among women living with HIV and diagnosed with cervical cancer. Methods: We conducted a population-based study using the National Inpatient Sample (NIS) database comprising hospitalized HIV-positive women with or without cervical cancer diagnosis, from 2003 through 2015. We compared trends in the rates of cervical cancer, in-hospital death, and years of potential life lost (YPLL) by race/ethnicity. Results: We identified 2,613,696 women with HIV, and among them, 5398 had cervical cancer. The prevalence of cervical cancer (per 10,000) was 9.3 for NH-Whites, 30.9 among NH-Blacks, and 30.2 for Hispanics. Rates of cervical cancer over time diminished significantly only among NH-Whites (average annual percent change (AAPC), − 5.8 (− 9.7, − 1.8)), and YPLL in women with cervical cancer decreased significantly only in NH-Whites (AAPC, − 6.2 (− 10.1, − 2.0)). Cervical cancer was associated with increased odds of in-hospital death overall (OR 2.24 (1.59–3.15)) and among NH-Blacks (OR 2.03 (1.30–3.18)) only. Conclusions: NH-Blacks and Hispanics with HIV remain at increased risk for concurrent diagnosis of cervical cancer compared with NH-Whites. Moreover, NH-Black women with HIV and cervical cancer are at greatest risk for in-hospital death. The findings emphasize the need for a more robust prevention strategy among minority women to reduce the high burden of HIV/cervical cancer and related mortality.

Original languageEnglish (US)
Pages (from-to)24-32
Number of pages9
JournalJournal of Racial and Ethnic Health Disparities
Volume8
Issue number1
DOIs
StatePublished - Feb 2021

Keywords

  • Cervical cancer
  • HIV
  • Healthcare disparities
  • Racial disparities

ASJC Scopus subject areas

  • Health(social science)
  • Anthropology
  • Sociology and Political Science
  • Health Policy
  • Public Health, Environmental and Occupational Health

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